| 4. Round | 15/08/2021 | FK Tuapse | - | Alania-2 Vladikavkaz | 3:1 | ||||
| 5. Round | 20/08/2021 | FK Tuapse | - | Kuban-Holding Pavlovskaya | 0:3 dec. | ||||
| 13. Round | 11/10/2021 | FK Yessentuki | - | FK Tuapse | 1:4 | ||||
| 14. Round | 18/10/2021 | FK Tuapse | - | FK Biolog Novokubansk | 0:3 dec. |  |
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| 15. Round | 23/10/2021 | FK Legion Dynamo Makhachkala | - | FK Tuapse | 0:1 | ||||
| 16. Round | 01/11/2021 | FK Tuapse | - | FK Mashuk KMV | 3:0 | |
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| 17. Round | 05/11/2021 | Spartak Nalchik | - | FK Tuapse | 1:1 | ||||
| 18. Round | 12/11/2021 | FK Tuapse | - | Anzhi Makhachkala | 1:1 | |
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| 19. Round | 19/11/2021 | FK Druzhba | - | FK Tuapse | 1:0 | ||||
| 29. Round | 06/05/2022 | FK Tuapse | - | FK Yessentuki | 3:0 | ||||
| 31. Round | 16/05/2022 | FK Tuapse | - | FK Legion Dynamo Makhachkala | 0:5 | ||||
| 32. Round | 22/05/2022 | FK Mashuk KMV | - | FK Tuapse | 1:3 | ||||
| 33. Round | 30/05/2022 | FK Tuapse | - | Spartak Nalchik | 0:4 | ||||
| 34. Round | 05/06/2022 | FK Chayka | - | FK Tuapse | 5:0 |
Russia