| 1. Round | 01/02/2025 | Defensor Sporting | - | Boston River | 2:0 | ||||
| 5. Round | 09/03/2025 | Progreso | - | Boston River | 2:2 | ||||
| 8. Round | 26/03/2025 | Plaza Colonia | - | Boston River | 0:1 | ||||
| 10. Round | 05/04/2025 | Juventud de Las Piedras | - | Boston River | 4:1 | ||||
| 11. Round | 13/04/2025 | Boston River | - | Cerro Largo | 1:0 |
Uruguay