| 4. Round | 26/02/2023 | Deportivo Maldonado | - | Boston River | 3:2 | ||||
| 6. Round | 11/03/2023 | Nacional | - | Boston River | 3:1 | ||||
| 7. Round | 19/03/2023 | Boston River | - | Danubio | 3:3 | ||||
| 8. Round | 26/03/2023 | Fénix | - | Boston River | 0:0 | ||||
| 9. Round | 02/04/2023 | Boston River | - | Montevideo Wanderers | 0:1 |  |
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| 12. Round | 22/04/2023 | Montevideo City Torque | - | Boston River | 1:1 | ||||
| 13. Round | 28/04/2023 | Boston River | - | Liverpool | 1:3 | ||||
| 14. Round | 05/05/2023 | Cerro Largo | - | Boston River | 2:2 |
Uruguay