| 1. Round | 28/07/2018 | KV Oostende | - | Royal Excel Mouscron | 2:1 |  |
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| 2. Round | 05/08/2018 | Royal Excel Mouscron | - | Club Brugge KV | 0:1 | ||||
| 3. Round | 11/08/2018 | Royal Excel Mouscron | - | Royal Antwerp FC | 0:1 | ||||
| 4. Round | 17/08/2018 | RSC Anderlecht | - | Royal Excel Mouscron | 2:0 | ||||
| 5. Round | 25/08/2018 | Royal Excel Mouscron | - | KAS Eupen | 0:1 | ||||
| 6. Round | 01/09/2018 | Sporting Charleroi | - | Royal Excel Mouscron | 3:1 | ||||
| 9. Round | 29/09/2018 | Royal Excel Mouscron | - | Waasland-Beveren | 0:3 | ||||
| 10. Round | 06/10/2018 | Sint-Truidense VV | - | Royal Excel Mouscron | 3:1 | |
Greece