| 3. Round | 11/08/2021 | Coyotes de Tlaxcala | - | Alebrijes de Oaxaca | 1:1 | ||||
| 4. Round | 18/08/2021 | Alebrijes de Oaxaca | - | Tepatitlán | 2:3 | ||||
| 5. Round | 29/08/2021 | Leones Negros | - | Alebrijes de Oaxaca | 1:1 | ||||
| 6. Round | 01/09/2021 | Alebrijes de Oaxaca | - | CF Monterrey II | 0:0 | ||||
| 7. Round | 09/09/2021 | Dorados de Sinaloa | - | Alebrijes de Oaxaca | 2:1 |
Mexico