| 2. Round | 30/07/2022 | FK SKA Rostov | - | FK Druzhba | 2:0 | ||||
| 3. Round | 07/08/2022 | FK Druzhba | - | FK Chayka | 0:1 | ||||
| 4. Round | 13/08/2022 | FK Yessentuki | - | FK Druzhba | 0:2 | ||||
| 5. Round | 21/08/2022 | FK Druzhba | - | Forte Taganrog | 1:2 |  |
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| 6. Round | 27/08/2022 | Spartak Nalchik | - | FK Druzhba | 1:1 | ||||
| 9. Round | 18/09/2022 | FK Druzhba | - | Kuban-Holding Pavlovskaya | 2:3 | ||||
| 10. Round | 25/09/2022 | Alania-2 Vladikavkaz | - | FK Druzhba | 1:3 | |
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| 11. Round | 01/10/2022 | FK Druzhba | - | FK Mashuk KMV | 0:1 | ||||
| 12. Round | 08/10/2022 | FK Druzhba | - | FK Legion Dynamo Makhachkala | 1:0 | ||||
| 13. Round | 15/10/2022 | Chernomorets Novorossisk | - | FK Druzhba | 6:1 | ||||
| 14. Round | 22/10/2022 | FK Druzhba | - | FK SKA Rostov | 1:0 | |
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| 15. Round | 29/10/2022 | FK Chayka | - | FK Druzhba | 1:0 | ||||
| 25. Round | 22/04/2023 | FK Druzhba | - | Chernomorets Novorossisk | 0:3 | ||||
| 26. Round | 29/04/2023 | Dinamo Stavropol | - | FK Druzhba | 0:2 |
Russia