| 4. Round | 18/07/2020 | Speranţa Nisporeni | - | Dinamo-Auto | 1:2 | ||||
| 5. Round | 22/07/2020 | FC Floreşti | - | Speranţa Nisporeni | 1:1 | ||||
| 7. Round | 31/07/2020 | Dacia Buiucani | - | Speranţa Nisporeni | 0:3 | ||||
| 14. Round | 16/10/2020 | Speranţa Nisporeni | - | FC Floreşti | 0:0 | ||||
| 16. Round | 25/10/2020 | Speranţa Nisporeni | - | Dacia Buiucani | 0:0 | ||||
| 17. Round | 31/10/2020 | Speranţa Nisporeni | - | FC Codru Lozova | 3:0 | ||||
| 18. Round | 06/11/2020 | FC Sfîntul Gheorghe | - | Speranţa Nisporeni | 1:0 | ||||
| 19. Round | 21/11/2020 | FC Sheriff | - | Speranţa Nisporeni | 3:0 |  |
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| 20. Round | 25/11/2020 | Speranţa Nisporeni | - | FC Zimbru | 2:2 | |
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| 21. Round | 20/02/2021 | FC Milsami | - | Speranţa Nisporeni | 3:0 | |
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| 27. Round | 11/04/2021 | Speranţa Nisporeni | - | FC Sfîntul Gheorghe | 0:3 | ||||
| 29. Round | 23/04/2021 | FC Zimbru | - | Speranţa Nisporeni | 6:0 |
Moldova
Romania