| 3. Round | 25/01/2025 | Mazatlán FC | - | Deportivo Toluca | 2:1 | ||||
| 4. Round | 29/01/2025 | Puebla FC | - | Mazatlán FC | 0:1 |  |
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| 5. Round | 01/02/2025 | Mazatlán FC | - | Club León | 1:2 | ||||
| 6. Round | 10/02/2025 | Pumas UNAM | - | Mazatlán FC | 1:0 | ||||
| 8. Round | 22/02/2025 | Club Necaxa | - | Mazatlán FC | 3:1 | |
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| 9. Round | 26/02/2025 | Mazatlán FC | - | CF Monterrey | 1:0 |  |
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| 10. Round | 01/03/2025 | Mazatlán FC | - | Cruz Azul | 1:1 | |
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| 12. Round | 15/03/2025 | Gallos Blancos | - | Mazatlán FC | 1:0 | ||||
| 13. Round | 29/03/2025 | Mazatlán FC | - | Atlas Guadalajara | 3:2 | |
Uruguay