| 18. Round | 22/01/2000 | NAC Breda | - | FC Zwolle | 2:0 | ||||
| 19. Round | 29/01/2000 | FC Zwolle | - | Heracles Almelo | 1:0 | ||||
| 20. Round | 05/02/2000 | BV Emmen | - | FC Zwolle | 0:2 | ||||
| 22. Round | 20/02/2000 | FC Groningen | - | FC Zwolle | 2:1 | ||||
| 23. Round | 26/02/2000 | FC Zwolle | - | FC Volendam | 2:2 | ||||
| 25. Round | 11/03/2000 | FC Zwolle | - | Helmond Sport | 3:2 | ||||
| 26. Round | 20/03/2000 | SBV Excelsior | - | FC Zwolle | 1:3 | ||||
| 27. Round | 25/03/2000 | FC Zwolle | - | RBC Roosendaal | 3:1 | ||||
| 28. Round | 03/04/2000 | SBV Eindhoven | - | FC Zwolle | 2:1 | ||||
| 29. Round | 08/04/2000 | FC Zwolle | - | Dordrecht '90 | 4:0 | ||||
| 31. Round | 22/04/2000 | ADO Den Haag | - | FC Zwolle | 2:3 | ||||
| 32. Round | 01/05/2000 | FC Zwolle | - | VVV | 4:0 | ||||
| 33. Round | 06/05/2000 | TOP Oss | - | FC Zwolle | 1:3 | ||||
| 34. Round | 13/05/2000 | FC Zwolle | - | Telstar | 3:3 |
Netherlands