| 2. Round | 02/08/2008 | Jaguares Chiapas | - | UANL Tigres | 1:3 |  |
|||
| 3. Round | 09/08/2008 | Club San Luis | - | Jaguares Chiapas | 2:0 | ||||
| 4. Round | 16/08/2008 | Jaguares Chiapas | - | Atlante | 1:1 |  |
|||
| 5. Round | 24/08/2008 | CF América | - | Jaguares Chiapas | 2:3 | |
|||
| 7. Round | 31/08/2008 | Puebla FC | - | Jaguares Chiapas | 1:1 | ||||
| 8. Round | 13/09/2008 | Jaguares Chiapas | - | Indios Juárez | 2:1 | ||||
| 12. Round | 11/10/2008 | Jaguares Chiapas | - | Club Necaxa | 4:0 | |
|||
| 14. Round | 25/10/2008 | Jaguares Chiapas | - | Deportivo Toluca | 0:0 |  |
|||
| 6. Round | 06/11/2008 | Jaguares Chiapas | - | Pumas UNAM | 0:3 |
Brazil