| 1. Round | 17/07/2016 | FO ŽP Šport Podbrezová | - | Spartak Trnava | 1:1 | ||||
| 2. Round | 24/07/2016 | Spartak Trnava | - | FC DAC 1904 | 2:1 | ||||
| 4. Round | 07/08/2016 | Spartak Trnava | - | MŠK Žilina | 1:2 | ||||
| 5. Round | 13/08/2016 | Spartak Trnava | - | 1. FC Tatran Prešov | 2:0 | ||||
| 6. Round | 20/08/2016 | Spartak Myjava | - | Spartak Trnava | annull. | ||||
| 7. Round | 27/08/2016 | Spartak Trnava | - | Slovan Bratislava | 0:0 | ||||
| 8. Round | 10/09/2016 | AS Trenčín | - | Spartak Trnava | 3:3 |  |
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| 10. Round | 24/09/2016 | FK Senica | - | Spartak Trnava | 0:1 | ||||
| 25. Round | 02/04/2017 | MFK Ružomberok | - | Spartak Trnava | 1:0 | ||||
| 26. Round | 09/04/2017 | Spartak Trnava | - | MŠK Žilina | 1:2 | ||||
| 27. Round | 16/04/2017 | Spartak Trnava | - | 1. FC Tatran Prešov | 4:0 | ||||
| 29. Round | 26/04/2017 | Spartak Trnava | - | Slovan Bratislava | 0:3 | ||||
| 30. Round | 07/05/2017 | AS Trenčín | - | Spartak Trnava | 3:4 | ||||
| 31. Round | 13/05/2017 | Spartak Trnava | - | MFK Zemplín Michalovce | 1:0 | ||||
| 32. Round | 19/05/2017 | FK Senica | - | Spartak Trnava | 1:0 | ||||
| 33. Round | 27/05/2017 | Spartak Trnava | - | Zlaté Moravce | 3:1 |
Slovakia