| Group 1 | 07/03/2021 | Sonsonate FC | - | Once Municipal | 0:1 | ||||
| Group 1 | 11/03/2021 | Sonsonate FC | - | FAS | 2:1 |  |
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| Group 1 | 14/03/2021 | Isidro Metapán | - | Sonsonate FC | 0:2 | ||||
| Group B | 21/03/2021 | Sonsonate FC | - | AD Chalatenango | 3:3 | ||||
| Group B | 31/03/2021 | CD Águila | - | Sonsonate FC | 4:0 | ||||
| Group B | 04/04/2021 | Sonsonate FC | - | Isidro Metapán | 0:1 | |
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| Group B | 08/04/2021 | Sonsonate FC | - | Municipal Limeño | 0:2 | ||||
| Group B | 22/04/2021 | Sonsonate FC | - | CD Águila | 0:1 | ||||
| Group B | 25/04/2021 | Isidro Metapán | - | Sonsonate FC | 5:2 | |
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| Group B | 28/04/2021 | Municipal Limeño | - | Sonsonate FC | 1:0 | ||||
| Group B | 01/05/2021 | Sonsonate FC | - | Santa Tecla FC | 2:1 |
Uruguay