| 1. Round | 05/08/2022 | sc Heerenveen | - | Sparta Rotterdam | 0:0 | ||||
| 2. Round | 13/08/2022 | Feyenoord | - | sc Heerenveen | 0:0 |  |
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| 3. Round | 20/08/2022 | Vitesse | - | sc Heerenveen | 0:4 | ||||
| 4. Round | 27/08/2022 | sc Heerenveen | - | Fortuna Sittard | 2:1 | ||||
| 5. Round | 04/09/2022 | sc Heerenveen | - | NEC Nijmegen | 0:0 | ||||
| 6. Round | 10/09/2022 | AFC Ajax | - | sc Heerenveen | 5:0 | ||||
| 7. Round | 18/09/2022 | sc Heerenveen | - | FC Twente | 2:1 | ||||
| 8. Round | 02/10/2022 | FC Emmen | - | sc Heerenveen | 0:0 | ||||
| 9. Round | 09/10/2022 | sc Heerenveen | - | PSV Eindhoven | 0:1 | ||||
| 10. Round | 15/10/2022 | Go Ahead Eagles | - | sc Heerenveen | 1:1 | ||||
| 11. Round | 23/10/2022 | FC Volendam | - | sc Heerenveen | 1:3 | ||||
| 12. Round | 29/10/2022 | sc Heerenveen | - | FC Utrecht | 1:2 | ||||
| 13. Round | 05/11/2022 | SBV Excelsior | - | sc Heerenveen | 0:1 | ||||
| 14. Round | 13/11/2022 | sc Heerenveen | - | SC Cambuur | 2:1 | ||||
| 15. Round | 07/01/2023 | RKC Waalwijk | - | sc Heerenveen | 0:0 | ||||
| 16. Round | 14/01/2023 | sc Heerenveen | - | AZ Alkmaar | 0:2 | ||||
| 17. Round | 22/01/2023 | sc Heerenveen | - | FC Groningen | 3:1 | ||||
| 34. Round | 28/05/2023 | sc Heerenveen | - | Go Ahead Eagles | 2:0 |
Netherlands