| 16. Round | 27/02/2021 | Kolos Kovalivka | - | Rukh Lviv | 1:2 | ||||
| 17. Round | 08/03/2021 | Rukh Lviv | - | Desna Chernigov | 0:4 | ||||
| 19. Round | 21/03/2021 | Dinamo Kiev | - | Rukh Lviv | 3:0 |  |
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| 20. Round | 03/04/2021 | Rukh Lviv | - | Zorya Lugansk | 0:2 | ||||
| 21. Round | 11/04/2021 | Rukh Lviv | - | FC Mynai | 2:0 | ||||
| 22. Round | 18/04/2021 | Inhulets Petrove | - | Rukh Lviv | 0:0 | |
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| 23. Round | 23/04/2021 | FK Mariupol | - | Rukh Lviv | 0:3 |  |
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| 18. Round | 28/04/2021 | FK Lviv | - | Rukh Lviv | 1:1 | ||||
| 24. Round | 02/05/2021 | Rukh Lviv | - | FK Oleksandriya | 2:1 | ||||
| 25. Round | 06/05/2021 | Rukh Lviv | - | Olimpik Donetsk | 3:0 | |
Ukraine