| 1. Round | 16/01/2022 | Montañeses FC | - | Deportivo Dongu | 3:0 | ||||
| 4. Round | 05/02/2022 | Deportivo Dongu | - | Yalmakan FC | 0:2 | ||||
| 5. Round | 13/02/2022 | Lobos ULMX | - | Deportivo Dongu | 2:0 | ||||
| 7. Round | 26/02/2022 | Deportivo Dongu | - | Inter Playa | 1:4 | ||||
| 8. Round | 05/03/2022 | Cañoneros FC | - | Deportivo Dongu | 1:0 | ||||
| 10. Round | 19/03/2022 | Escorpiones | - | Deportivo Dongu | 5:3 |
Mexico