| 21. Round | 04/02/2011 | Borussia Dortmund | - | FC Schalke 04 | 0:0 | ||||
| 22. Round | 12/02/2011 | FC Schalke 04 | - | SC Freiburg | 1:0 | ||||
| 23. Round | 20/02/2011 | Bor. Mönchengladbach | - | FC Schalke 04 | 2:1 | ||||
| 24. Round | 26/02/2011 | FC Schalke 04 | - | 1. FC Nürnberg | 1:1 | ||||
| 26. Round | 12/03/2011 | FC Schalke 04 | - | Eintracht Frankfurt | 2:1 | ||||
| 27. Round | 20/03/2011 | Bayer Leverkusen | - | FC Schalke 04 | 2:0 |  |
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| 29. Round | 09/04/2011 | FC Schalke 04 | - | VfL Wolfsburg | 1:0 | ||||
| 30. Round | 16/04/2011 | Werder Bremen | - | FC Schalke 04 | 1:1 | |
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| 32. Round | 30/04/2011 | Bayern München | - | FC Schalke 04 | 4:1 |
Ghana