| 1. Round | 15/04/2022 | Guayaquil City [U19] | - | 9 de Octubre [U19] | 1:2 | ||||
| 2. Round | 22/04/2022 | Delfín SC [U19] | - | Guayaquil City [U19] | 1:2 | ||||
| 3. Round | 07/05/2022 | Guayaquil City [U19] | - | Emelec [U19] | 3:1 | ||||
| 5. Round | 28/05/2022 | Atlético Santo Domingo [U19] | - | Guayaquil City [U19] | 0:1 | ||||
| 6. Round | 04/06/2022 | 9 de Octubre [U19] | - | Guayaquil City [U19] | 0:3 | ||||
| 10. Round | 05/08/2022 | Guayaquil City [U19] | - | Atlético Santo Domingo [U19] | 0:1 |  |
Ecuador