| 5. Round | 15/08/2020 | Deportivo Guadalajara | - | Atlético San Luis | 2:1 | ||||
| 8. Round | 06/09/2020 | UANL Tigres | - | Deportivo Guadalajara | 1:3 | ||||
| 12. Round | 26/09/2020 | Deportivo Guadalajara | - | Mazatlán FC | 2:1 | ||||
| 13. Round | 05/10/2020 | Club Tijuana | - | Deportivo Guadalajara | 0:0 | ||||
| 14. Round | 18/10/2020 | Deportivo Guadalajara | - | Atlas Guadalajara | 3:2 |  |
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| 17. Round | 07/11/2020 | Deportivo Guadalajara | - | CF Monterrey | 3:1 |
Mexico