| 2. Round | 20/08/2021 | Manchester City U23 | - | Blackburn Rovers U23 | 4:2 | ||||
| 5. Round | 17/09/2021 | Blackburn Rovers U23 | - | Tottenham Hotspur U23 | 3:3 | ||||
| 9. Round | 25/10/2021 | Blackburn Rovers U23 | - | Liverpool FC U23 | 2:2 | ||||
| 18. Round | 24/01/2022 | Blackburn Rovers U23 | - | Leeds United U23 | 4:0 | ||||
| 20. Round | 20/02/2022 | Liverpool FC U23 | - | Blackburn Rovers U23 | 1:1 | ||||
| 22. Round | 14/03/2022 | Arsenal FC U23 | - | Blackburn Rovers U23 | 2:2 | ||||
| 21. Round | 08/04/2022 | Blackburn Rovers U23 | - | West Ham United U23 | 2:0 |
Greece