| 1. Round | 18/07/2021 | Zvezda St. Petersburg | - | Baltika Kaliningrad 2 | 2:1 |  |
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| 6. Round | 21/08/2021 | FK Tver | - | Baltika Kaliningrad 2 | 1:0 | ||||
| 7. Round | 30/08/2021 | Baltika Kaliningrad 2 | - | FK Leningradets | 0:1 | ||||
| 11. Round | 18/09/2021 | Zenit St. Petersburg 2 | - | Baltika Kaliningrad 2 | 2:1 | ||||
| 13. Round | 30/09/2021 | FK Kairat Moskva | - | Baltika Kaliningrad 2 | 1:3 |  |
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| 16. Round | 14/10/2021 | Baltika Kaliningrad 2 | - | FK Tver | 1:2 | ||||
| 17. Round | 19/10/2021 | FK Leningradets | - | Baltika Kaliningrad 2 | 2:0 | ||||
| 21. Round | 10/11/2021 | Baltika Kaliningrad 2 | - | Zenit St. Petersburg 2 | 2:1 | |
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| 22. Round | 14/11/2021 | Baltika Kaliningrad 2 | - | Zvezda St. Petersburg | 1:2 |
Russia