| 2. Round | 15/03/2025 | Miami FC | - | Indy Eleven | 1:3 |  |
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| 3. Round | 22/03/2025 | Lexington SC | - | Indy Eleven | 1:1 | ||||
| 4. Round | 29/03/2025 | Indy Eleven | - | Colorado Springs Switchbacks | 2:3 | |
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| 5. Round | 06/04/2025 | Indy Eleven | - | North Carolina FC | 2:2 |  |
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| 7. Round | 20/04/2025 | Indy Eleven | - | Charleston Battery | 1:3 | ||||
| 8. Round | 04/05/2025 | Indy Eleven | - | Detroit City FC | 2:2 | |
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| 9. Round | 11/05/2025 | Sacramento Republic | - | Indy Eleven | 1:1 | ||||
| 10. Round | 17/05/2025 | El Paso Locomotive | - | Indy Eleven | 3:1 |
USA