| 4. Round | 05/02/2022 | Alacranes de Durango | - | Catedráticos Elite | 6:0 |  |
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| 7. Round | 26/02/2022 | Tecos Fútbol Club | - | Alacranes de Durango | 0:2 | ||||
| 8. Round | 05/03/2022 | Alacranes de Durango | - | Colima FC | 6:1 | ||||
| 9. Round | 12/03/2022 | Leones Negros II | - | Alacranes de Durango | 2:4 | ||||
| 13. Round | 09/04/2022 | Correcaminos UAT II | - | Alacranes de Durango | 0:4 |
Mexico