| 1. Round | 04/02/2012 | Libertad | - | Club Nacional | 1:0 | ||||
| 5. Round | 03/03/2012 | Sol de América | - | Libertad | 0:3 |  |
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| 6. Round | 09/03/2012 | Libertad | - | Club Olimpia | 0:1 | ||||
| 7. Round | 17/03/2012 | Cerro Porteño | - | Libertad | 1:0 | ||||
| 8. Round | 25/03/2012 | Libertad | - | Sportivo Carapeguá | 1:1 |  |
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| 9. Round | 31/03/2012 | Cerro de Franco | - | Libertad | 0:2 | ||||
| 10. Round | 08/04/2012 | Libertad | - | Independiente CG | 1:1 | ||||
| 11. Round | 16/04/2012 | Club Rubio Ñu | - | Libertad | 1:5 | |
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| 13. Round | 22/04/2012 | Sportivo Luqueño | - | Libertad | 0:4 | |
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| 16. Round | 12/05/2012 | Libertad | - | Sol de América | 0:1 | ||||
| 12. Round | 06/06/2012 | Club Nacional | - | Libertad | 1:2 | ||||
| 17. Round | 12/06/2012 | Club Olimpia | - | Libertad | 2:1 | |
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| 18. Round | 17/06/2012 | Libertad | - | Cerro Porteño | 2:1 | ||||
| 19. Round | 26/06/2012 | Sportivo Carapeguá | - | Libertad | 2:2 | |
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| 20. Round | 01/07/2012 | Libertad | - | Cerro de Franco | 2:0 | |
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| 21. Round | 04/07/2012 | Independiente CG | - | Libertad | 1:4 | ||||
| 22. Round | 07/07/2012 | Libertad | - | Club Rubio Ñu | 1:0 | |
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Paraguay