| 1. Round | 24/07/2021 | FK Yessentuki | - | FK Biolog Novokubansk | 0:5 | ||||
| 3. Round | 07/08/2021 | FK Biolog Novokubansk | - | FK Legion Dynamo Makhachkala | 0:0 | ||||
| 4. Round | 15/08/2021 | FK Mashuk KMV | - | FK Biolog Novokubansk | 2:0 |  |
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| 5. Round | 18/08/2021 | FK Biolog Novokubansk | - | Spartak Nalchik | 1:0 | |
Russia