| 7. Round | 01/10/2021 | Hartford Athletic | - | Charlotte Independence | 1:2 | ||||
| 7. Round | 07/10/2021 | New Mexico United | - | Hartford Athletic | 2:2 | ||||
| 7. Round | 10/10/2021 | Charleston Battery | - | Hartford Athletic | 4:3 | ||||
| 7. Round | 14/10/2021 | Loudoun United | - | Hartford Athletic | 2:3 | ||||
| 7. Round | 17/10/2021 | Hartford Athletic | - | Loudoun United | 1:0 | ||||
| 7. Round | 31/10/2021 | Pittsburgh Riverhounds | - | Hartford Athletic | 0:0 |
USA