| 1. Round | 08/02/2008 | San Lorenzo | - | Newell's Old Boys | 0:2 | ||||
| 2. Round | 16/02/2008 | San Lorenzo | - | San Martín de San Juan | 0:1 | ||||
| 3. Round | 24/02/2008 | River Plate | - | San Lorenzo | 2:0 | ||||
| 5. Round | 07/03/2008 | Racing Club | - | San Lorenzo | 0:1 |  |
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| 7. Round | 21/03/2008 | Arsenal de Sarandí | - | San Lorenzo | 0:1 | ||||
| 8. Round | 30/03/2008 | San Lorenzo | - | Lanús | 3:1 | ||||
| 9. Round | 06/04/2008 | Tigre | - | San Lorenzo | 1:5 |  |
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| 11. Round | 20/04/2008 | Argentinos Juniors | - | San Lorenzo | 2:1 | |
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| 6. Round | 23/04/2008 | San Lorenzo | - | Vélez Sarsfield | 1:0 | ||||
| 12. Round | 27/04/2008 | San Lorenzo | - | Boca Juniors | 1:0 | ||||
| 15. Round | 18/05/2008 | Huracán | - | San Lorenzo | 0:0 | ||||
| 16. Round | 25/05/2008 | San Lorenzo | - | Colón de Santa Fe | 2:1 | |
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