| 1. Round | 10/02/2023 | Cobreloa | - | San Marcos | 2:1 | ||||
| 2. Round | 17/02/2023 | San Marcos | - | Deportes Iquique | 2:3 |  |
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| 3. Round | 28/02/2023 | Santiago Morning | - | San Marcos | 2:1 |  |
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| 4. Round | 04/03/2023 | San Marcos | - | Unión San Felipe | 0:2 | ||||
| 5. Round | 10/03/2023 | Recoleta | - | San Marcos | 1:1 | |
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| 6. Round | 20/03/2023 | San Marcos | - | San Luis | 1:0 | |
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| 7. Round | 27/03/2023 | Rangers | - | San Marcos | 4:2 | |
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| 8. Round | 17/04/2023 | San Marcos | - | La Serena | 2:1 | |
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| 9. Round | 23/04/2023 | Deportes Temuco | - | San Marcos | 1:1 | ||||
| 10. Round | 04/05/2023 | San Marcos | - | Universidad de Concepción | 5:0 | |
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| 11. Round | 10/05/2023 | Santiago Wanderers | - | San Marcos | 1:1 | ||||
| 17. Round | 08/07/2023 | Deportes Iquique | - | San Marcos | 2:1 | ||||
| 18. Round | 16/07/2023 | San Marcos | - | Santiago Morning | 2:2 | |
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| 19. Round | 22/07/2023 | Unión San Felipe | - | San Marcos | 3:0 | ||||
| 20. Round | 29/07/2023 | San Marcos | - | Recoleta | 3:2 | |
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| 25. Round | 04/09/2023 | Universidad de Concepción | - | San Marcos | 2:1 | ||||
| 26. Round | 11/09/2023 | San Marcos | - | Santiago Wanderers | 1:2 | ||||
| 27. Round | 24/09/2023 | Puerto Montt | - | San Marcos | 1:1 | |
Chile