| 1. Round | 28/07/2012 | KV Kortrijk | - | RSC Anderlecht | 1:1 |  |
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| 2. Round | 04/08/2012 | RSC Anderlecht | - | Beerschot AC | 1:0 | ||||
| 3. Round | 12/08/2012 | Cercle Brugge | - | RSC Anderlecht | 0:3 | ||||
| 4. Round | 18/08/2012 | RSC Anderlecht | - | RAEC Mons | 2:1 | ||||
| 6. Round | 02/09/2012 | RSC Anderlecht | - | KRC Genk | 2:2 | ||||
| 12. Round | 27/10/2012 | Sporting Charleroi | - | RSC Anderlecht | 2:0 | ||||
| 14. Round | 03/11/2012 | KV Mechelen | - | RSC Anderlecht | 1:4 | |
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| 15. Round | 11/11/2012 | RSC Anderlecht | - | Club Brugge KV | 6:1 | ||||
| 16. Round | 18/11/2012 | RSC Anderlecht | - | KV Kortrijk | 1:0 | ||||
| 18. Round | 01/12/2012 | RSC Anderlecht | - | Cercle Brugge | 2:1 | ||||
| 20. Round | 16/12/2012 | RSC Anderlecht | - | Oud-Heverlee Leuven | 2:1 | ||||
| 21. Round | 23/12/2012 | KRC Genk | - | RSC Anderlecht | 2:4 | ||||
| 22. Round | 27/12/2012 | RSC Anderlecht | - | Lierse SK (old) | 4:1 | ||||
| 23. Round | 27/02/2013 | RSC Anderlecht | - | SV Zulte Waregem | 0:1 |
Iran