| 1. Round | 11/01/2025 | Atlético San Luis | - | UANL Tigres | 1:3 | ||||
| 3. Round | 25/01/2025 | Atlético San Luis | - | Club Necaxa | 0:3 | ||||
| 5. Round | 03/02/2025 | Atlético San Luis | - | Pumas UNAM | 2:3 | ||||
| 8. Round | 23/02/2025 | CF Monterrey | - | Atlético San Luis | 3:1 | ||||
| 10. Round | 03/03/2025 | Atlas Guadalajara | - | Atlético San Luis | 3:1 | ||||
| 11. Round | 08/03/2025 | Atlético San Luis | - | FC Juárez | 1:0 | ||||
| 14. Round | 06/04/2025 | Atlético San Luis | - | Mazatlán FC | 2:1 | ||||
| 16. Round | 17/04/2025 | Atlético San Luis | - | Deportivo Toluca | 0:1 |
Mexico
Chile