| 7. Round | 02/10/2021 | Sint-Truidense VV [U18] | - | KAA Gent [U18] | 0:6 | ||||
| 8. Round | 09/10/2021 | KAA Gent [U18] | - | Sporting Charleroi [U18] | 2:0 | ||||
| 12. Round | 13/11/2021 | Royal Antwerp FC [U18] | - | KAA Gent [U18] | 4:1 | ||||
| 3. Round | 17/11/2021 | Standard Liège [U18] | - | KAA Gent [U18] | 0:1 |  |
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| 15. Round | 15/01/2022 | KVC Westerlo [U18] | - | KAA Gent [U18] | 1:2 | ||||
| 16. Round | 22/01/2022 | KAA Gent [U18] | - | Oud-Heverlee Leuven [U18] | 1:0 | ||||
| 18. Round | 05/02/2022 | KAA Gent [U18] | - | RSC Anderlecht [U18] | 0:1 | ||||
| 19. Round | 12/02/2022 | KV Mechelen [U18] | - | KAA Gent [U18] | 2:3 | ||||
| 17. Round | 16/02/2022 | Club Brugge KV [U18] | - | KAA Gent [U18] | 6:2 | ||||
| 22. Round | 12/03/2022 | KAA Gent [U18] | - | SV Zulte Waregem [U18] | 0:1 | ||||
| 23. Round | 19/03/2022 | KAA Gent [U18] | - | KRC Genk [U18] | 2:3 | ||||
| 25. Round | 02/04/2022 | KAA Gent [U18] | - | Royal Antwerp FC [U18] | 4:0 | ||||
| 26. Round | 23/04/2022 | Cercle Brugge [U18] | - | KAA Gent [U18] | 1:1 |
Belgium