| 6. Round | 07/09/2007 | SC Cambuur | - | FC Volendam | 2:1 | ||||
| 7. Round | 14/09/2007 | SC Cambuur | - | RBC Roosendaal | 2:2 | ||||
| 8. Round | 17/09/2007 | FC Omniworld | - | SC Cambuur | 1:2 |  |
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| 10. Round | 30/09/2007 | TOP Oss | - | SC Cambuur | 3:2 | ||||
| 11. Round | 05/10/2007 | Stormvogels Telstar | - | SC Cambuur | 1:2 | |
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| 12. Round | 12/10/2007 | SC Cambuur | - | Go Ahead Eagles | 0:2 | |
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| 16. Round | 09/11/2007 | FC Zwolle | - | SC Cambuur | 4:1 | |
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| 17. Round | 16/11/2007 | SC Cambuur | - | HFC Haarlem | 1:3 | ||||
| 18. Round | 23/11/2007 | FC Emmen | - | SC Cambuur | 2:0 | |
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| 20. Round | 07/12/2007 | FC Dordrecht | - | SC Cambuur | 2:3 | ||||
| 23. Round | 11/01/2008 | SC Cambuur | - | FC Omniworld | 1:0 | ||||
| 24. Round | 18/01/2008 | RBC Roosendaal | - | SC Cambuur | 1:0 | ||||
| 25. Round | 25/01/2008 | AGOVV | - | SC Cambuur | 2:2 | ||||
| 26. Round | 01/02/2008 | SC Cambuur | - | FC Zwolle | 1:1 | ||||
| 27. Round | 08/02/2008 | SC Cambuur | - | TOP Oss | 1:2 | ||||
| 28. Round | 15/02/2008 | FC Eindhoven | - | SC Cambuur | 2:1 | ||||
| 29. Round | 22/02/2008 | BV Veendam | - | SC Cambuur | 4:4 | |
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| 35. Round | 28/03/2008 | Fortuna Sittard | - | SC Cambuur | 2:0 | |
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| 37. Round | 11/04/2008 | SC Cambuur | - | Helmond Sport | 5:1 | ||||
| 38. Round | 18/04/2008 | MVV | - | SC Cambuur | 2:2 |
Netherlands