| 1. Round | 21/07/2012 | CSKA Moskva | - | FK Rostov | 1:0 | ||||
| 2. Round | 29/07/2012 | FK Rostov | - | Anzhi Makhachkala | 2:2 | ||||
| 3. Round | 03/08/2012 | Mordovia Saransk | - | FK Rostov | 3:0 | ||||
| 5. Round | 18/08/2012 | FK Krasnodar | - | FK Rostov | 0:0 | ||||
| 7. Round | 01/09/2012 | Volga Nizhniy Novgorod | - | FK Rostov | 1:1 | ||||
| 8. Round | 16/09/2012 | FK Rostov | - | Dinamo Moskva | 1:0 |  |
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| 12. Round | 21/10/2012 | FK Rostov | - | Lokomotiv Moskva | 0:0 | ||||
| 13. Round | 26/10/2012 | Kuban Krasnodar (1928-2018) | - | FK Rostov | 1:0 | ||||
| 14. Round | 02/11/2012 | Zenit St. Petersburg | - | FK Rostov | 2:1 | ||||
| 15. Round | 09/11/2012 | FK Rostov | - | FK Amkar Perm | 3:0 | ||||
| 16. Round | 18/11/2012 | Anzhi Makhachkala | - | FK Rostov | 0:0 | ||||
| 17. Round | 23/11/2012 | FK Rostov | - | Mordovia Saransk | 2:0 | ||||
| 18. Round | 02/12/2012 | Krylia Sovetov | - | FK Rostov | 0:2 | ||||
| 19. Round | 07/12/2012 | FK Rostov | - | FK Krasnodar | 2:3 |
Cameroon