| 1. Round | 17/08/2008 | KAA Gent | - | RAEC Mons | 5:0 | ||||
| 2. Round | 23/08/2008 | RSC Anderlecht | - | KAA Gent | 2:2 | ||||
| 3. Round | 31/08/2008 | KAA Gent | - | Sporting Charleroi | 2:0 |  |
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| 4. Round | 13/09/2008 | Excelsior Mouscron | - | KAA Gent | 4:2 | ||||
| 5. Round | 20/09/2008 | KAA Gent | - | KV Mechelen | 1:2 | ||||
| 6. Round | 28/09/2008 | Germinal Beerschot | - | KAA Gent | 2:2 | ||||
| 7. Round | 04/10/2008 | KAA Gent | - | Sporting Lokeren | 1:1 | ||||
| 8. Round | 18/10/2008 | AFC Tubize | - | KAA Gent | 0:1 | ||||
| 9. Round | 26/10/2008 | KAA Gent | - | Club Brugge KV | 3:0 | ||||
| 10. Round | 02/11/2008 | SV Zulte Waregem | - | KAA Gent | 0:2 | ||||
| 11. Round | 08/11/2008 | KAA Gent | - | FCV Dender EH | 1:1 | |
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| 12. Round | 14/11/2008 | KVC Westerlo | - | KAA Gent | 3:2 | |
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| 13. Round | 23/11/2008 | KAA Gent | - | KRC Genk | 2:3 | ||||
| 14. Round | 29/11/2008 | KAA Gent | - | KSV Roeselare | 4:0 |
Belgium