1. Round | 25/07/2021 | Desna Chernigov | - | Chernomorets Odessa | 3:0 | ||||
3. Round | 06/08/2021 | Metalist 1925 Kharkiv | - | Chernomorets Odessa | 3:2 | ||||
4. Round | 16/08/2021 | FK Mariupol | - | Chernomorets Odessa | 2:3 | ||||
5. Round | 21/08/2021 | Chernomorets Odessa | - | Shakhtar Donetsk | 0:3 | ||||
14. Round | 06/11/2021 | Chernomorets Odessa | - | Rukh Lviv | 4:3 | ||||
15. Round | 19/11/2021 | Chernomorets Odessa | - | Dinamo Kiev | 1:6 | ||||
18. Round | 12/12/2021 | Chernomorets Odessa | - | Metalist 1925 Kharkiv | 2:1 |