| 1. Round | 24/08/2022 | Rukh Lviv | - | Metalist Kharkiv | 1:2 | ||||
| 2. Round | 28/08/2022 | Kolos Kovalivka | - | Rukh Lviv | 2:0 | ||||
| 3. Round | 02/09/2022 | Rukh Lviv | - | Shakhtar Donetsk | 0:1 | ||||
| 4. Round | 09/09/2022 | Rukh Lviv | - | Zorya Lugansk | 3:1 | ||||
| 5. Round | 30/09/2022 | NK Veres | - | Rukh Lviv | 2:2 | ||||
| 6. Round | 09/10/2022 | Dinamo Kiev | - | Rukh Lviv | 3:0 | ||||
| 7. Round | 16/10/2022 | Rukh Lviv | - | SK Dnipro-1 | 2:3 | ||||
| 8. Round | 19/10/2022 | Vorskla Poltava | - | Rukh Lviv | 0:1 | ||||
| 9. Round | 23/10/2022 | Rukh Lviv | - | Metalist 1925 Kharkiv | 1:1 | ||||
| 11. Round | 06/11/2022 | Rukh Lviv | - | Kryvbas Kryvyi Rih | 2:1 | ||||
| 12. Round | 10/11/2022 | FK Lviv | - | Rukh Lviv | 2:1 |  |
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Ukraine