| 20. Round | 21/08/2021 | FK Gomel | - | Dinamo Minsk | 2:0 | ||||
| 21. Round | 28/08/2021 | Torpedo-BelAZ Zhodino | - | FK Gomel | 0:1 |  |
|||
| 22. Round | 11/09/2021 | FK Gomel | - | FK Vitebsk | 4:1 | ||||
| 23. Round | 18/09/2021 | FK Slutsk | - | FK Gomel | 1:4 | ||||
| 24. Round | 24/09/2021 | FK Gomel | - | Dinamo Brest | 0:0 | ||||
| 25. Round | 02/10/2021 | FK Gomel | - | FK Slaviya Mozyr | 3:0 | ||||
| 26. Round | 17/10/2021 | FK Minsk | - | FK Gomel | 0:0 | ||||
| 27. Round | 23/10/2021 | FK Gomel | - | Energetik-BGU Minsk | 4:0 |  |
|||
| 28. Round | 07/11/2021 | FK Isloch Minsk | - | FK Gomel | 1:2 | ||||
| 29. Round | 20/11/2021 | FK Gomel | - | FK Smorgon | 0:0 | ||||
| 30. Round | 28/11/2021 | Shakhter Soligorsk | - | FK Gomel | 0:1 |
Ukraine