| 2. Round | 08/07/2022 | Club Tijuana [U20] | - | FC Juárez [U20] | 1:1 | ||||
| 4. Round | 23/07/2022 | Club Tijuana [U20] | - | CF América [U20] | 3:3 | ||||
| 5. Round | 26/07/2022 | Atlas Guadalajara [U20] | - | Club Tijuana [U20] | 4:1 | ||||
| 6. Round | 30/07/2022 | Club Tijuana [U20] | - | Mazatlán FC [U20] | 1:1 | ||||
| 8. Round | 12/08/2022 | Club Tijuana [U20] | - | Puebla FC [U20] | 3:4 |
Mexico