| 7. Round | 31/10/2020 | AFC Ajax | - | Fortuna Sittard | 5:2 |  |
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| 11. Round | 05/12/2020 | AFC Ajax | - | FC Twente | 1:2 | ||||
| 17. Round | 17/01/2021 | AFC Ajax | - | Feyenoord | 1:0 | ||||
| 19. Round | 28/01/2021 | AFC Ajax | - | Willem II | 3:1 | |
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| 20. Round | 31/01/2021 | AZ Alkmaar | - | AFC Ajax | 0:3 | ||||
| 23. Round | 21/02/2021 | AFC Ajax | - | Sparta Rotterdam | 4:2 | ||||
| 24. Round | 28/02/2021 | PSV Eindhoven | - | AFC Ajax | 1:1 | ||||
| 27. Round | 21/03/2021 | AFC Ajax | - | ADO Den Haag | 5:0 | |
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| 28. Round | 04/04/2021 | sc Heerenveen | - | AFC Ajax | 1:2 | ||||
| 21. Round | 22/04/2021 | AFC Ajax | - | FC Utrecht | 1:1 | ||||
| 30. Round | 25/04/2021 | AFC Ajax | - | AZ Alkmaar | 2:0 | ||||
| 34. Round | 16/05/2021 | Vitesse | - | AFC Ajax | 1:3 |
Netherlands
Ghana 