| 4. Round | 02/02/2020 | Real Potosí | - | Real Santa Cruz | 2:1 | ||||
| 5. Round | 09/02/2020 | Real Potosí | - | Club San José | 2:1 |  |
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| 13. Round | 27/11/2020 | Real Potosí | - | CD Guabirá | 0:1 | ||||
| 14. Round | 01/12/2020 | Real Potosí | - | Club Aurora | 2:1 | ||||
| 16. Round | 06/12/2020 | Real Potosí | - | The Strongest | 3:5 | |
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| 17. Round | 09/12/2020 | Real Santa Cruz | - | Real Potosí | 3:1 | ||||
| 18. Round | 11/12/2020 | Club San José | - | Real Potosí | 1:2 | |
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| 19. Round | 15/12/2020 | Real Potosí | - | Always Ready | 3:5 | ||||
| 21. Round | 21/12/2020 | Oriente Petrolero | - | Real Potosí | 2:0 | ||||
| 22. Round | 22/12/2020 | Atlético Palmaflor | - | Real Potosí | 0:0 | ||||
| 23. Round | 25/12/2020 | Real Potosí | - | Bolívar | 2:3 | |
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| 24. Round | 27/12/2020 | Royal Pari | - | Real Potosí | 1:1 | ||||
| 25. Round | 29/12/2020 | Real Potosí | - | Nacional Potosí | 2:3 | ||||
| 26. Round | 31/12/2020 | CD Guabirá | - | Real Potosí | 4:0 |
Bolivia