| Group B | 22/02/2023 | CD Guabirá | - | Real Santa Cruz | 0:1 | ||||
| Group B | 26/04/2023 | Real Santa Cruz | - | Club Aurora | 0:1 | ||||
| Group B | 11/07/2023 | Atlético Palmaflor | - | Real Santa Cruz | 0:0 | ||||
| Group B | 20/07/2023 | Real Santa Cruz | - | The Strongest | 1:1 | ||||
| Group B | 10/08/2023 | Real Santa Cruz | - | CD Guabirá | 1:3 | ||||
| Group B | 01/11/2023 | The Strongest | - | Real Santa Cruz | 4:0 |  |
Spain