| 1. Round | 15/02/2015 | Defensor Sporting | - | Nacional | 0:0 | ||||
| 2. Round | 22/02/2015 | Rentistas | - | Defensor Sporting | 2:6 |  |
|||
| 3. Round | 07/03/2015 | Defensor Sporting | - | Fénix | 1:0 | |
|||
| 4. Round | 15/03/2015 | Peñarol | - | Defensor Sporting | 2:0 | ||||
| 5. Round | 21/03/2015 | Defensor Sporting | - | CA Cerro | 1:1 |  |
|||
| 6. Round | 29/03/2015 | Juventud de Las Piedras | - | Defensor Sporting | 5:0 | ||||
| 7. Round | 05/04/2015 | Defensor Sporting | - | Tacuarembó | 1:0 | ||||
| 8. Round | 12/04/2015 | Defensor Sporting | - | Racing | 2:1 | |
|||
| 9. Round | 18/04/2015 | Sud América | - | Defensor Sporting | 0:0 | |
|||
| 10. Round | 26/04/2015 | Defensor Sporting | - | El Tanque Sisley | 2:2 | ||||
| 11. Round | 03/05/2015 | River Plate | - | Defensor Sporting | 1:2 | ||||
| 12. Round | 16/05/2015 | Defensor Sporting | - | Danubio | 1:1 | ||||
| 13. Round | 24/05/2015 | Atenas | - | Defensor Sporting | 1:2 | ||||
| 14. Round | 30/05/2015 | Defensor Sporting | - | Montevideo Wanderers | 2:0 | |
|||
| 15. Round | 07/06/2015 | Rampla Juniors | - | Defensor Sporting | 0:0 |
Uruguay