| 4. Round | 11/06/2012 | Vancouver Whitecaps | - | Houston Dynamo | 3:1 | ||||
| 4. Round | 21/06/2012 | Houston Dynamo | - | Toronto FC | 3:3 | ||||
| 4. Round | 24/06/2012 | Impact de Montréal | - | Houston Dynamo | 4:2 | ||||
| 4. Round | 01/07/2012 | Houston Dynamo | - | Philadelphia Union | 2:1 | ||||
| 5. Round | 04/07/2012 | Houston Dynamo | - | Chicago Fire | 0:0 | ||||
| 5. Round | 08/07/2012 | Sporting Kansas City | - | Houston Dynamo | 0:0 | ||||
| 5. Round | 19/07/2012 | Houston Dynamo | - | Sporting Kansas City | 2:1 | ||||
| 8. Round | 21/10/2012 | Houston Dynamo | - | Philadelphia Union | 3:1 |
USA