| 3. Round | 11/07/2022 | Jorge Wilstermann | - | Universitario de Vinto | 2:0 | ||||
| 4. Round | 15/07/2022 | Jorge Wilstermann | - | CD Guabirá | 2:2 | ||||
| 6. Round | 29/07/2022 | Blooming | - | Jorge Wilstermann | 0:1 | ||||
| 7. Round | 31/07/2022 | Jorge Wilstermann | - | Real Tomayapo | 0:2 | ||||
| 16. Round | 08/09/2022 | Atlético Palmaflor | - | Jorge Wilstermann | 1:1 | ||||
| 17. Round | 11/09/2022 | Jorge Wilstermann | - | The Strongest | 0:3 | ||||
| 18. Round | 18/09/2022 | Universitario de Vinto | - | Jorge Wilstermann | 0:0 |  |
|||
| 19. Round | 01/10/2022 | CD Guabirá | - | Jorge Wilstermann | 1:1 | ||||
| 20. Round | 05/10/2022 | Jorge Wilstermann | - | Bolívar | 1:1 | ||||
| 21. Round | 10/10/2022 | Jorge Wilstermann | - | Blooming | 1:0 | ||||
| 22. Round | 14/10/2022 | Real Tomayapo | - | Jorge Wilstermann | 1:0 | |
|||
| 23. Round | 17/10/2022 | Jorge Wilstermann | - | Independiente Petrolero | 1:3 | ||||
| 24. Round | 22/10/2022 | Oriente Petrolero | - | Jorge Wilstermann | 2:1 |
Bolivia