| 1. Round | 23/08/1980 | Sparta Rotterdam | - | Feyenoord | 1:2 | ||||
| 2. Round | 26/08/1980 | Feyenoord | - | Willem II | 4:0 | ||||
| 4. Round | 02/09/1980 | Go Ahead Eagles | - | Feyenoord | 0:2 | ||||
| 6. Round | 20/09/1980 | FC Wageningen | - | Feyenoord | 0:1 | ||||
| 7. Round | 26/09/1980 | Feyenoord | - | NAC Breda | 4:0 | ||||
| 8. Round | 04/10/1980 | PSV Eindhoven | - | Feyenoord | 0:1 | ||||
| 9. Round | 18/10/1980 | Feyenoord | - | SBV Excelsior | 2:0 | ||||
| 10. Round | 26/10/1980 | FC Groningen | - | Feyenoord | 0:0 |  |
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| 11. Round | 31/10/1980 | Feyenoord | - | FC Den Haag | 4:1 | ||||
| 12. Round | 07/11/1980 | AZ '67 Alkmaar | - | Feyenoord | 5:2 | ||||
| 16. Round | 12/12/1980 | MVV | - | Feyenoord | 0:0 | ||||
| 18. Round | 31/01/1981 | Feyenoord | - | Sparta Rotterdam | 2:2 | ||||
| 19. Round | 07/02/1981 | Willem II | - | Feyenoord | 1:2 |  |
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| 20. Round | 14/02/1981 | FC Utrecht | - | Feyenoord | 2:0 | |
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| 27. Round | 17/04/1981 | Feyenoord | - | FC Groningen | 3:3 | ||||
| 29. Round | 02/05/1981 | Feyenoord | - | AZ '67 Alkmaar | 1:5 | ||||
| 30. Round | 08/05/1981 | PEC Zwolle | - | Feyenoord | 2:2 | |
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| 31. Round | 16/05/1981 | Feyenoord | - | SC NEC | 1:1 | ||||
| 33. Round | 29/05/1981 | Feyenoord | - | MVV | 4:2 | |
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| 34. Round | 05/06/1981 | FC Twente | - | Feyenoord | 3:7 |
Netherlands