| 1. Round | 07/01/2023 | CF Monterrey [U18] | - | Deportivo Guadalajara [U18] | 1:0 | ||||
| 2. Round | 13/01/2023 | Atlético San Luis [U18] | - | Deportivo Guadalajara [U18] | 3:2 | ||||
| 3. Round | 21/01/2023 | Deportivo Guadalajara [U18] | - | Deportivo Toluca [U18] | 1:2 |  |
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| 4. Round | 28/01/2023 | FC Juárez [U18] | - | Deportivo Guadalajara [U18] | 3:3 | ||||
| 5. Round | 05/02/2023 | Deportivo Guadalajara [U18] | - | Gallos Blancos [U18] | 4:0 | ||||
| 6. Round | 11/02/2023 | CF Pachuca [U18] | - | Deportivo Guadalajara [U18] | 2:2 | |
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| 7. Round | 15/02/2023 | Deportivo Guadalajara [U18] | - | Club Tijuana [U18] | 1:2 | ||||
| 8. Round | 18/02/2023 | Pumas UNAM [U18] | - | Deportivo Guadalajara [U18] | 0:1 | ||||
| 10. Round | 04/03/2023 | Deportivo Guadalajara [U18] | - | Santos Laguna [U18] | 2:0 | ||||
| 11. Round | 10/03/2023 | Puebla FC [U18] | - | Deportivo Guadalajara [U18] | 2:0 | |
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| 12. Round | 18/03/2023 | Deportivo Guadalajara [U18] | - | CF América [U18] | 4:1 | |
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| 13. Round | 01/04/2023 | Atlas Guadalajara [U18] | - | Deportivo Guadalajara [U18] | 2:3 |
Mexico