| 6. Round | 23/08/2020 | Club Tijuana [U20] | - | Puebla FC [U20] | 1:1 | ||||
| 7. Round | 28/08/2020 | Puebla FC [U20] | - | Deportivo Toluca [U20] | 0:0 | ||||
| 8. Round | 04/09/2020 | Pumas UNAM [U20] | - | Puebla FC [U20] | 2:0 | ||||
| 9. Round | 08/09/2020 | Puebla FC [U20] | - | CF América [U20] | 3:1 | ||||
| 10. Round | 11/09/2020 | FC Juárez [U20] | - | Puebla FC [U20] | 2:0 | ||||
| 11. Round | 18/09/2020 | Club Necaxa [U20] | - | Puebla FC [U20] | 1:1 | ||||
| 1. Round | 11/10/2020 | Mazatlán FC [U20] | - | Puebla FC [U20] | 1:2 | ||||
| 14. Round | 17/10/2020 | CF Monterrey [U20] | - | Puebla FC [U20] | 3:1 | ||||
| 17. Round | 06/11/2020 | Puebla FC [U20] | - | Atlético San Luis [U20] | 2:1 |
Mexico