| 3. Round | 07/02/2018 | Club San José | - | Royal Pari | 3:0 | ||||
| 4. Round | 17/02/2018 | Sport Boys Warnes | - | Club San José | 0:0 | ||||
| 5. Round | 25/02/2018 | Club San José | - | Blooming | 4:0 | ||||
| 6. Round | 03/03/2018 | Club Aurora | - | Club San José | 1:1 | ||||
| 8. Round | 14/03/2018 | Nacional Potosí | - | Club San José | 2:2 | ||||
| 9. Round | 18/03/2018 | Club San José | - | The Strongest | 3:1 |  |
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| 7. Round | 25/03/2018 | Club San José | - | Universitario de Sucre | 2:1 | ||||
| 10. Round | 31/03/2018 | Royal Pari | - | Club San José | 0:2 | |
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| 11. Round | 08/04/2018 | Club San José | - | Sport Boys Warnes | 4:0 | ||||
| 12. Round | 16/04/2018 | Blooming | - | Club San José | 0:1 | ||||
| 13. Round | 22/04/2018 | Club San José | - | Club Aurora | 3:2 | ||||
| 14. Round | 29/04/2018 | Universitario de Sucre | - | Club San José | 1:2 |
Argentina