| 4. Round | 30/01/2011 | Monarcas Morelia | - | Club San Luis | 3:3 | ||||
| 14. Round | 03/02/2011 | CF América | - | Club San Luis | 3:0 | ||||
| 5. Round | 06/02/2011 | Club San Luis | - | Estudiantes Tecos | 3:2 | ||||
| 6. Round | 13/02/2011 | Atlante | - | Club San Luis | 0:0 |  |
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| 7. Round | 19/02/2011 | Club San Luis | - | Pumas UNAM | 0:1 | ||||
| 13. Round | 10/04/2011 | Club San Luis | - | Club Necaxa | 0:0 |
Mexico