| 1. Round | 22/08/2010 | Liverpool | - | Rampla Juniors | 3:1 | ||||
| 2. Round | 29/08/2010 | Defensor Sporting | - | Liverpool | 3:0 | ||||
| 3. Round | 05/09/2010 | Liverpool | - | Racing | 1:0 |  |
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| 4. Round | 19/09/2010 | Tacuarembó | - | Liverpool | 3:2 |  |
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| 6. Round | 03/10/2010 | Nacional | - | Liverpool | 0:0 | ||||
| 7. Round | 09/10/2010 | Liverpool | - | Central Español | 2:2 | |
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| 14. Round | 28/11/2010 | Liverpool | - | Montevideo Wanderers | 0:2 | |
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| 15. Round | 04/12/2010 | CA Cerro | - | Liverpool | 2:1 |  |
Uruguay