| 5. Round | 07/02/2016 | Puebla FC | - | Atlas Guadalajara | 4:1 | ||||
| 6. Round | 15/02/2016 | CF Pachuca | - | Puebla FC | 5:2 | ||||
| 9. Round | 06/03/2016 | Puebla FC | - | CD Veracruz | 1:1 | ||||
| 10. Round | 12/03/2016 | Cruz Azul | - | Puebla FC | 1:1 | ||||
| 11. Round | 20/03/2016 | Puebla FC | - | UANL Tigres | 0:0 | ||||
| 12. Round | 03/04/2016 | Monarcas Morelia | - | Puebla FC | 2:0 | ||||
| 14. Round | 17/04/2016 | Club León | - | Puebla FC | 4:1 | ||||
| 16. Round | 30/04/2016 | Club Tijuana | - | Puebla FC | 0:0 |
Mexico